(GLOBE NEWSWIRE) — In a letter to Gov. Doug Ducey of Arizona, the Association of American Physicians and Surgeons (AAPS) presents a frequently updated table of studies that report results of treating COVID-19 with the anti-malaria drugs chloroquine (CQ) and hydroxychloroquine (HCQ, Plaquenil®).
To date, the total number of reported patients treated with HCQ, with or without zinc and the widely used antibiotic azithromycin, is 2,333, writes AAPS, in observational data from China, France, South Korea, Algeria, and the U.S. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.
The antiviral properties of these drugs have been studied since 2003. Particularly when combined with zinc, they hinder viral entry into cells and inhibit replication. They may also prevent overreaction by the immune system, which causes the cytokine storm responsible for much of the damage in severe cases, explains AAPS. HCQ is often very helpful in treating autoimmune diseases such as lupus and rheumatoid arthritis.
This is a news release excerpt from AAPS.
Dr. Fauci: Remdesivir has ‘significant effect’ on diminishing COVID recovery time
“It is a very important proof of concept because what it is proving is that a drug can block this virus,” Fauci added. “The mortality rate trended towards being better in the sense of less deaths in the remdesivir group – 8 percent versus 11 percent in the placebo group. It has not reached statistical significance but the data needs to be further analyzed.”
“But I think it’s really opening the door to the fact that we now have the capability of treating, and I can guarantee you, as more people, more companies, more investigators get involved, it’s going to get better and better,” said Fauci.
Excerpt from Fox News.
Dear Governor Ducey:
This concerns your Executive Order forbidding prophylactic use of chloroquine (CQ) or hydroxychloroquine (HCQ) unless peer-reviewed evidence becomes available.
Attached and posted here (https://bit.ly/cqhcqresearch) is a summary of peer-reviewed evidence, indexed in PubMed, concerning the use of CQ and HCQ against coronavirus. We believe that there is clear and convincing evidence of benefit both pre-exposure and post-exposure.
In addition, Michael J. A. Robb, M.D., of Phoenix is compiling all reports as they come in. As of this date, the total number of reported patients treated with HCQ, with or without azithromycin and zinc, is 2,333. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.
Most of the data concerns use of HCQ for treatment, but one study included used the medication as prophylaxis with excellent results. Many nations, including Turkey and India, are protecting medical workers and contacts of infected persons prophylactically.
Read the rest of the letter